Soft Tissue Repair

Restoring Function. Enhancing Healing. Rethinking Soft Tissue Repair.

Soft tissue repair refers to the restoration of soft tissues damaged by trauma, disease, or surgical intervention. Applications range from hernia and pelvic floor reconstructions to breast reconstruction and complex soft tissue defects, such as those resulting from urogenital disorders. Mesh implants play a vital role by providing mechanical stability and supporting the body’s natural healing process.

While biologically degradable meshes and autologous grafts are either limited in availability or associated with high costs, synthetic meshes are a widespread alternative. However, their long-term integration is often challenged by insufficient biocompatibility and foreign body reactions. Successful treatment requires implants that combine high biocompatibility, mechanical stability, and optimal tissue integration to sustainably restore function and aesthetics.

Challenges in
Soft Tissue Repair

Conventional mesh implants made from synthetic materials often exhibit insufficient biocompatibility, which can lead to chronic foreign body reactions and persistent inflammation. Many of these meshes also have smooth and hydrophobic surfaces that impair cell adhesion and vascularization. This hampers integration into the surrounding tissue and can negatively affect both the structural and functional integrity of the implant. In addition, mechanical stress can cause microcracks in the material, further aggravating inflammatory processes and leading to increased revision rates.

Our Innovative Solution

With our innovative, elastic titanium mesh technology, we offer optimized mesh structures for soft tissue repair applications.

Long-Term Stability

Titanium is highly resistant to corrosion, primarily due to the formation of a stable titanium dioxide (TiO₂) layer. This natural barrier protects the material from degradation – even under harsh physiological conditions – and ensures exceptional long-term structural integrity. Our elastic titanium mesh implants maintain their mechanical strength and shape over time, unlike synthetic meshes, which may lose up to 20% of their strength annually. With no signs of aging or embrittlement, titanium offers a reliable and durable solution for long-term implantation, ensuring consistent mechanical performance throughout the implant’s lifespan.

Dynamic Adaptability

Titanium is not only strong but also highly flexible. Our elastic mesh implants made of titanium microthreads adapt dynamically to the body’s natural movements. Unlike rigid or brittle synthetic materials, titanium retains its form and function even under repetitive mechanical load. This combination of elasticity and durability reduces mechanical irritation and contributes to superior long-term comfort and implant integration. The result is a material that supports tissue healing while offering a high degree of mechanical resilience tailored to the demands of soft tissue reconstruction.

Low Risk of Infection

Titanium naturally forms an oxide layer that significantly reduces bacterial adhesion and lowers the risk of postoperative infections. Unlike many synthetic materials, its surface properties actively contribute to a less hospitable environment for pathogens. Research shows that titanium’s surface roughness can influence bacterial colonization. Targeted surface modifications – such as nanoscale structuring, silver doping, or polymer coatings – can further enhance the antimicrobial potential of titanium, offering an added layer of protection, especially in complex or contaminated surgical settings.

Tissue Integration

Titanium exhibits a unique ability to interact with both bone and soft tissue. Its hydrophilic surface properties support direct protein adsorption, facilitating cellular adhesion and neovascularization. This promotes rapid tissue ingrowth and stable anchoring of the implant. Advanced surface treatments – such as increased hydrophilicity or nanoscale structuring – can further boost regenerative responses. Compared to conventional materials, titanium demonstrates higher cell vitality and superior biological integration, making it a compelling choice for applications that require seamless tissue-implant interaction.

Biocompatibility

As one of the most biocompatible materials in medicine, titanium is exceptionally well tolerated by the human body. Its stable oxide layer minimizes inflammatory responses and significantly reduces foreign body reactions. In contrast to polymers or coated metals, titanium remains biologically inert even over extended periods. Specialized surface treatments, including hydrophilic or nanostructured modifications, can modulate immune response and help prevent excessive fibrotic encapsulation. The result is a consistently high level of tissue compatibility and long-term implant safety.

Areas of Indication

Wählen Sie einen der Punkte aus um unterhalb des Bildes Informationen zu erhalten.

Overview

With proven clinical use across more than 20 medical indications - from soft tissue repair to complex bone reconstruction - our titanium mesh implants are backed by clinical studies involving almost 4,000 patients, including nearly 2,000 treated with TiSilk.

Numerous peer-reviewed publications confirm excellent outcomes, low complication rates, and superior tissue integration compared to synthetic materials.

Our solutions are used across a broad range of disciplines, including:

- Dentistry & Orthodontics

- Cardiovascular & Thoracic Surgery

- Reconstructive & Plastic Surgery

- General Surgery

- Urogynecology

- Orthopedics & Traumatology

Click on a section of the image to explore more details.

Dentistry & Orthodontics

Mesh implants are specifically used to stabilize and regenerate bone and soft tissue structures in the oral cavity. TiSilk® mesh implants and Titanell® suture material have proven clinically effective in guided bone regeneration, dental implantology, and periodontal therapy. They promote new bone formation, enhance implant stability, and support long-term function and aesthetics.

Titanium forms a direct, stable bond with living bone — without the need for adhesives. Its excellent biocompatibility, low infection risk, and natural tissue integration provide a strong foundation for lasting therapeutic success.

Cardiovascular & Thoracic Surgery

Titanium mesh implants are now considered the gold standard for reconstructing the chest wall and sternum following surgical procedures or infections. They provide structural support after sternotomies, tumor resections, or serve as scaffolds for bone healing.

Studies have shown that thoracoplasty using TiSilk® meshes in cases of sternal instability due to chronic postoperative sterno-mediastinitis leads to successful chest wall stabilization, significant pain reduction, and complete absence of recurrence. Titanium alloys are also widely used in heart valves and stents—their excellent biocompatibility and high mechanical stability ensure long-term functionality within dynamic cardiac structures.

Reconstructive & Plastic Surgery

TiSilk® meshes are used for the reconstruction of soft tissue structures following trauma, tumor resections, or aesthetic procedures. In breast reconstruction, they serve as a stable matrix for regenerating tissue and enable natural shaping with long-term durability. Thanks to their excellent biocompatibility and stability, they support tissue integration and reduce complications compared to synthetic materials.

Studies confirm the successful use of TiSilk® for treating post-traumatic adhesions in the facial area, for static ptosis correction, and in reconstructive procedures related to facial nerve palsy. Results show high patient satisfaction, stable aesthetic outcomes, and low complication rates.

General Surgery

TiSilk® mesh implants are primarily used in visceral surgery for the treatment of inguinal, incisional, and abdominal wall hernias. They stabilize soft tissue, reduce the risk of recurrence, and enable durable reconstruction due to their high strength. Thanks to their elastic structure, they adapt to natural tissue movement.

Clinical studies involving over 1,000 patients have shown that, compared to conventional meshes, TiSilk® implants are associated with reduced inflammatory response, lower complication rates, improved tissue integration, and minimal shrinkage.

Urogynecology

TiSilk® mesh implants offer a promising alternative to synthetic materials in pelvic floor surgery. They provide excellent tissue integration, reduced inflammatory response, and a lower risk of erosion and infection.

Studies involving over 600 patients confirm their successful use in prolapse surgeries and the treatment of stress urinary incontinence — demonstrating stable long-term outcomes and fewer complications compared to conventional meshes.

Orthopedics & Traumatology

TiSilk® mesh implants are used in orthopedics and traumatology for the reconstruction of tendons, soft tissues, and bone defects. They offer mechanical stability, support tissue integration, and help reduce the risk of inflammation and postoperative complications. Studies have shown promising results in tendon repair, defect coverage after spinal surgery, and in orthopedic oncology—for example, in the fixation of muscle insertions following tumor resections.

Polyfilament Titanell® suture material has also proven effective in trauma surgery. It enables secure adaptation of tendons, joint capsules, and bone structures while reducing the risk of postoperative infections. Its inert properties help minimize inflammation, making it particularly suitable for use in high-risk patients.

Product Highlights

Our elastic titanium-based implants combine stability, flexibility and biocompatibility, supporting functional tissue repair across a wide range of surgical indications – with long-lasting positive clinical outcomes.

TiSilk® Sleeve

TiSilk® sleeves, tubes and tapes, designed for use in pelvic floor and reconstructive surgery.

Learn more

TiSilk® Mesh

TiSilk® meshes for usage in reconstructive soft tissue surgery including hernia repair, pelvic floor reconstruction, guided bone regeneration in dental surgery.

Learn more